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Argentina Wine Itinerary: Mendoza, Cafayate & Patagonia

Duration:11 nights
Argentina Wine Itinerary: Mendoza, Cafayate & Patagonia

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Accommodation

2 nights in Buenos Aires

3 nights in Mendoza

3 nights in Cafayate

1 night in Salta

2 nights in Neuquen

Flight - Day 2

Buenos Aires Mendoza

Flight - Day 5

Mendoza Salta

Flight - Day 9

SaltaNeuquen

Flight - Day 11

NeuquenBuenos Aires

Transfers

All transfers

Description

Sip your way across Argentina on a 12-day journey through its top wine regions. Start in Mendoza, where Malbec thrives under the Andes sun; continue to Cafayate, home to high-altitude Torrontés and red canyons; and finish in Patagonia’s Neuquén, producing elegant cool-climate Pinot Noir and Chardonnay. Smart routing, curated tastings, and breathtaking landscapes make this itinerary the perfect blend of wine, culture, and nature — from mountain to desert to steppe.  

Travel itinerary

Día 1

Arrival in Buenos Aires

Arrive in Buenos Aires, Argentina’s vibrant capital.  
Free afternoon to explore Palermo or Recoleta, ideal areas for cafés and parks.  
Optional: Enjoy a wine bar introduction to Argentine varietals — perfect warm-up before heading west.  

Día 2

To the Andes: Buenos Aires ✈ Mendoza

Morning flight (~1h50) to Mendoza, at the foot of the Andes.  
Afternoon visit to Catena Zapata or Pulenta Estate for an overview of local terroirs.  
Learn how altitude and glacial irrigation define Malbec’s style.  
Optional: Sunset tasting with Andes views.

Día 3

Uco Valley Highlights

Día 4

Vineyard Culture & Relaxed Mendoza Day

Día 5

Northbound: Mendoza ✈ Salta → Cafayate

Día 6

Cafayate’s Torrontés & Altitude Reds

Día 7

Calchaquí Valley Boutique Bodegas

Día 8

Return to Salta City

Día 9

South to Patagonia: Salta ✈ Neuquén

Día 10

Neuquén’s Cool-Climate Wines

Día 11

Return to Buenos Aires ✈

Día 12

Departure

Transfer to the airport for international flight.  
Check airline rules for carrying bottles or arrange winery shipment.  
Optional: Quick café stop before departure.

Key details

⚠️ Practical & Safety Notes  

  • Altitude: Cafayate sits ~1,700 m; stay hydrated, avoid over-tasting on arrival.  
  • Sun exposure: Very strong in Salta and Uco; SPF 50, hat, and sunglasses advised.  
  • Cash & cards: Credit cards accepted at most wineries; small cash for rural stops.  
  • Roads: Good condition overall, but signage can be minimal — avoid night driving.  
  • Health: Tap water safe in cities; bottled recommended in rural areas.  

Plan your trip effortlessly with our agents

Planning item 1

We create the plan and quote tailored to you

We talk about each traveler's preferences to give you the best options for flights, accommodations, and experiences.

Planning item 2

We manage the bookings and you get your travel guide

You choose the travel proposal you like, and we manage the bookings. We create your guide with all the information and itinerary.

Planning item 3

Enjoy your trip from the idea to your return

We provide support during the trip for needs or inquiries. We advise you via chat, call, or at our office in CABA.

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